Roxane Pouliot

• Centre de recherche ARThrite
• Centre de recherche du CHU de Québec - Université Laval
• Centre de recherche en arthrite
• Centre de recherche en organogenèse expérimentale

• Marissa Bélanger, Maîtrise en sciences pharmaceutiques - avec mémoire
• Andréa Tremblay, Doctorat en sciences pharmaceutiques
• Mahamane Rayane Abdoulaye Harouna, Maîtrise en sciences pharmaceutiques - avec mémoire
• Anthony Bernard, Maîtrise en sciences pharmaceutiques - avec mémoire

Encadrements terminés dans les 5 dernières années

• Yasmine Ruel, Doctorat en sciences pharmaceutiques
• Emmy Jean, Maîtrise en sciences pharmaceutiques - avec mémoire
• Sophie Morin, Doctorat en sciences pharmaceutiques
• Florence Turgeon, Maîtrise en sciences pharmaceutiques - avec mémoire
• Sarah Bélanger, Maîtrise en sciences pharmaceutiques - avec mémoire
• Camille Grenier, Maîtrise en sciences pharmaceutiques - avec mémoire
• Justine Matthey-de-L'Endroit, Maîtrise en sciences pharmaceutiques - avec mémoire
• Geneviève Rioux, Doctorat en sciences pharmaceutiques
• Yasmine Ruel, Maîtrise en sciences pharmaceutiques - avec mémoire
• Alexe Grenier, Doctorat en sciences pharmaceutiques
• Ariane Pineau, Maîtrise en sciences pharmaceutiques - avec mémoire
• Andréa Tremblay, Maîtrise en sciences pharmaceutiques - avec mémoire

Publications des 5 dernières années

Toward Long-Acting Psoriasis Therapy with Phloretin-Loaded Microneedle Patches: Insights from In Vitro Patient-Derived Skin Models, ACS Pharmacology & Translational Science, 2025. Yasmine Ruel, Fatma Moawad, Emmy Jean, Catherine Nadeau, Jérôme Alsarraf, André Pichette, Jean Legault, Davide Brambilla, Roxane Pouliot. DOI 10.1021/acsptsci.5c00361

Sensory neurons increase keratinocyte proliferation through CGRP release in a tissue engineered in vitro model of innervation in psoriasis, Acta Biomaterialia, 2024. Rémy Pepin, Julien Ringuet, Marie-Josée Beaudet, Sabrina Bellenfant, Todd Galbraith, Hélène Veillette, Roxane Pouliot, François Berthod. DOI 10.1016/j.actbio.2024.05.021

Antiproliferative and Anti-Inflammatory Effects of the Polyphenols Phloretin and Balsacone C in a Coculture of T Cells and Psoriatic Keratinocytes, International Journal of Molecular Sciences, 2024. Yasmine Ruel, Fatma Moawad, Jérôme Alsarraf, André Pichette, Jean Legault, Davide Brambilla, Roxane Pouliot. DOI 10.3390/ijms25115639

Impact of the crystal size of crystalline active pharmaceutical compounds on loading into microneedles, International Journal of Pharmaceutics, 2024. Fatma Moawad, Marion Le Meur, Yasmine Ruel, Valérie Gaëlle Roullin, Roxane Pouliot, Davide Brambilla. DOI 10.1016/j.ijpharm.2023.123676

Eicosapentaenoic Acid Influences the Lipid Profile of an In Vitro Psoriatic Skin Model Produced with T Cells, Biomolecules, 2023. Sophie Morin, Andréa Tremblay, Elizabeth Dumais, Pierre Julien, Nicolas Flamand, Roxane Pouliot. DOI 10.3390/biom13091413

Toxic Interaction Between Solar Radiation and Cigarette Smoke on Primary Human Keratinocytes, Photochemistry and Photobiology, 2023. Alexe Grenier, Mathieu C. Morissette, Patrick J. Rochette, Roxane Pouliot. DOI 10.1111/php.13768

Gene Profiling of a 3D Psoriatic Skin Model Enriched in T Cells: Downregulation of PTPRM Promotes Keratinocyte Proliferation through Excessive ERK1/2 Signaling, Cells, 2022. Geneviève Rioux, Florence Turgeon, Gaëtan Le-Bel, Camille Grenier, Sylvain L. Guérin, Roxane Pouliot. DOI 10.3390/cells11182904

Alpha-Linolenic Acid Modulates T Cell Incorporation in a 3D Tissue-Engineered Psoriatic Skin Model, Cells, 2022. Sophie Morin, Mélissa Simard, Geneviève Rioux, Pierre Julien, Roxane Pouliot. DOI 10.3390/cells11091513

α-Linolenic acid and linoleic acid modulate the lipidome and the skin barrier of a tissue-engineered skin model, Acta Biomaterialia, 2022. Mélissa Simard, Andréa Tremblay, Sophie Morin, Cyril Martin, Pierre Julien, Julie Fradette, Nicolas Flamand, Roxane Pouliot. DOI 10.1016/j.actbio.2021.11.021

Docosahexaenoic Acid Modulates Paracellular Absorption of Testosterone and Claudin-1 Expression in a Tissue-Engineered Skin Model, International Journal of Molecular Sciences, 2021. Andréa Tremblay, Mélissa Simard, Sophie Morin, Roxane Pouliot. DOI 10.3390/ijms222313091

Development of a 3D psoriatic skin model optimized for infiltration of IL-17A producing T cells: Focus on the crosstalk between T cells and psoriatic keratinocytes, Acta Biomaterialia, 2021. Geneviève Rioux, Mélissa Simard, Sophie Morin, Isabelle Lorthois, Sylvain L. Guérin, Roxane Pouliot. DOI 10.1016/j.actbio.2021.09.018

Investigation of Omega-3 Polyunsaturated Fatty Acid Biological Activity in a Tissue-Engineered Skin Model Involving Psoriatic Cells, Journal of Investigative Dermatology, 2021. Mélissa Simard, Geneviève Rioux, Sophie Morin, Cyril Martin, Sylvain L. Guérin, Nicolas Flamand, Pierre Julien, Julie Fradette, Roxane Pouliot. DOI 10.1016/j.jid.2021.02.755

Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils, Cells, 2021. Anne-Sophie Archambault, Francesco Tinto, Élizabeth Dumais, Volatiana Rakotoarivelo, Magdalena Kostrzewa, Pier-Luc Plante, Cyril Martin, Mélissa Simard, Cristoforo Silvestri, Roxane Pouliot, Michel Laviolette, Louis-Philippe Boulet, Rosa Maria Vitale, Alessia Ligresti, Vincenzo Di Marzo, Nicolas Flamand. DOI 10.3390/cells10092322

Antioxidant, Anti-Inflammatory, and Anti-Aging Potential of a Kalmia angustifolia Extract and Identification of Some Major Compounds, Antioxidants, 2021. Alexe Grenier, Jean Legault, André Pichette, Lorry Jean, Audrey Bélanger, Roxane Pouliot. DOI 10.3390/antiox10091373